Empirical research on the ethics of genomic research
نویسندگان
چکیده
There is no universally accepted definition of what an incidental finding is [Wolf et al., ] and broadly speaking this could include variants of known and unknown clinical significance, variants linked to highly penetrant, serious, life-threatening conditions, non-paternity or ancestry data. For the purposes of our study, we have adopted a pragmatic distinction between ‘pertinent’ and ‘incidental’ findings as set out in this text. Whilst in the US definitions of incidental findings are becoming accepted in practice [Green et al., ] it is still not known how and whether these also apply elsewhere around the world. Grant sponsor: Health Innovation Challenge Fund; Grant number: HICF-1009-003; Grant sponsor: Cambridge South REC; Grant number: 10/H0305/83; Grant sponsor: Republic of Ireland REC; Grant number: GEN/284/12. Correspondence to: Anna Middleton, Wellcome Trust Sanger Institute, Genome Campus, Hinxton, Cambridge CB10 1SA, UK. E-mail: [email protected] Article first published online in Wiley Online Library (wileyonlinelibrary.com): 27 June 2013 DOI 10.1002/ajmg.a.36067 TO THE EDITOR:
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